Взаимосвязь структурных преобразований щитовидной, паращитовидной и репаративной регенерации костной ткани при гипо- и гиперкальциемии

Abstract

With hypocalcemia, PTH synthesis is enhanced, which increases the osteolytic activity of osteoblasts and osteocytes, activating osteocytic osteolysis, stimulates the movement of osteoclasts to the site of resorption and their activity [1, 3]. With hypercalcemia, according to the feedback principle, the synthesis of calcitonin increases, which stimulates the flow of calcium and phosphorus from the blood into the bones, accelerates the deposition of calcium, inhibits its release from the bones, promotes the formation of an organic matrix, the process of its mineralization, accelerates the process of osteogenesis, increases bone strength.