Modulation of IncRNA H19 enhances resveratrol‐inhibited cancer cell proliferation and migration by regulating endoplasmic reticulum stress
Bibliographic entry
Zhang, Xinyue. Modulation of IncRNA H19 enhances resveratrol‐inhibited cancer cell proliferation and migration by regulating endoplasmic reticulum stress / Xinyue Zhang, Kunpeng Zhou, Yanlin Li // Новые горизонты - 2022 : сборник материалов IX Белорусско-Китайского молодежного инновационного форума, 10-11 ноября 2022 года / Белорусский национальный технический университет. – Минск : БНТУ, 2022. – Т. 1. – С. 197-198.
Abstract
The phytoalexin resveratrol exhibits anti-tumour activity in many types of cancer. In this study, we showed that resveratrol suppressed the survival of gastric tumour cells both in vivo and in vitro. Resveratrol promoted apoptosis, autophagy and endoplasmic reticulum (ER) stress in a dosedependent manner. In conclusion, resveratrol inhibited cancer cell survival, while knockdown of lncRNA H19 resulted in increased sensitivity to resveratrol therapy.