三种复合益生菌对菌群失调模型小鼠补偿生长和免疫功能的影响

Abstract

To investigate the effects of three kinds of compound probiotics on compensation growth and immune function in dysbacteriosis mice, the mice model of antibiotic-associated dysbacteriosis was utilized in this study. These mice were divided into four groups, Group (intragastric administration of bacterium), Group (intragastric administration of bacterium), Group (intragastric administration of bacterium), as well as the normal and model control groups without receiving any probiotics, with a trial period of 30 days. The mice received five consecutive intramuscular injections with 40 mg/Kg hydrocortisone every other day since day 20 to induce immunosuppression. These results suggested that mice feeding with the compound probiotics (Ⅰ or Ⅱ) were able to significantly alleviate stress, compensate growth and enhance immunity of dysbacteriosis‐immunosuppression, comparing with the mice in model control group. This study provides a basis for facilitating the growth and enhancing the immunity in the livestock and poultry.